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Scientific References:

  1. Adler SM, Verbalis JG. Disorders of body water homeostasis in critical illness.Endocrinol Metab Clin North Am. 2006 Dec;35(4):873-894, xi. doi:10.1016/j.ecl.2006.09.011.
  2. De Backer D, Creteur J, Vincent JL. Arginine vasopressin in advanced vasodilatory shock. Circulation. 2003 Nov 11;108(19):e142-. doi:10.1161/01.CIR.0000066692.71008.
  3. Gentilin A, Zanini P, Cevese A, Schena F, Tarperi C. Ergogenic effects of citrulline supplementation on exercise performance and physiological indexes of exercise performance during cycling tests: A review. Science & Sports. 2022 Dec 1;37(8):665-674. doi:10.1016/j.scispo.2021.12.011.
  4. Ginni A the A. Fluid retention can signal slow metabolism [Internet]. 2018 [cited 2024 Apr 13].
  5. Harvard Health. Fluid retention: What it can mean for your heart [Internet]. 2019 [cited 2024 Apr 13].
  6. Rathnavelu V, Alitheen NB, Sohila S, Kanagesan S, Ramesh R. Potential role of bromelain in clinical and therapeutic applications. Biomedical reports. 2016 Sep 1;5(3):283-288. doi: 10.3892/br.2016.720
  7. Morita M, Kobayashi Y, Iizuka M, Kondo S, Morishita K. The effect of oral L-citrulline supplementation on swelling of the lower legs in young females. Jpn Pharmacol Ther. 2012;40(9):787-794.
  1. Ramadan MF. Nutritional value, functional properties and nutraceutical applications of black cumin (Nigella sativa L.): an overview. International journal of food science & technology. 2007 Oct;42(10):1208-1218. doi:10.1111/j.1365-2621.2006.01417.x.
  2. Hunimed Web Team. The importance of drinking water to treat swollen legs and feet [Internet]. 2019 [cited 2024 Apr 13].
  3. Sapian S, Ibrahim Mze AA, Jubaidi FF, Mohd Nor NA, Taib IS, Abd Hamid Z, Zainalabidin S, Mohamad Anuar NN, Katas H, Latip J, Jalil J, Abu Bakar NF, Budin SB. Therapeutic Potential of Hibiscus sabdariffa Linn. In Attenuating Cardiovascular Risk Factors. Pharmaceuticals (Basel). 2023 May 29;16(6):807. doi:10.3390/ph16060807.
  4. Shepherd AI, Costello JT, Bailey SJ, Bishop N, Wadley AJ, Young-Min S, Gilchrist M, Mayes H, White D, Gorczynski P, Saynor ZL. “Beet” the cold: beetroot juice supplementation improves peripheral blood flow, endothelial function, and anti-inflammatory status in individuals with Raynaud’s phenomenon. Journal of applied physiology. 2019 Nov 1; 127(5): 1478–1490. doi:10.1152/japplphysiol.00292.2019
  5. Yimer EM, Tuem KB, Karim A, Ur-Rehman N, Anwar F. Nigella sativa L. (Black Cumin): A Promising Natural Remedy for Wide Range of Illnesses. Evidence-Based Complementary and Alternative Medicine. 2019 May 12;2019:1528635. doi:10.1155/2019/1528635.

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